Install Steam
login
|
language
简体中文 (Simplified Chinese)
繁體中文 (Traditional Chinese)
日本語 (Japanese)
한국어 (Korean)
ไทย (Thai)
Български (Bulgarian)
Čeština (Czech)
Dansk (Danish)
Deutsch (German)
Español - España (Spanish - Spain)
Español - Latinoamérica (Spanish - Latin America)
Ελληνικά (Greek)
Français (French)
Italiano (Italian)
Bahasa Indonesia (Indonesian)
Magyar (Hungarian)
Nederlands (Dutch)
Norsk (Norwegian)
Polski (Polish)
Português (Portuguese - Portugal)
Português - Brasil (Portuguese - Brazil)
Română (Romanian)
Русский (Russian)
Suomi (Finnish)
Svenska (Swedish)
Türkçe (Turkish)
Tiếng Việt (Vietnamese)
Українська (Ukrainian)
Report a translation problem
Step 1: Dissolve 10g of **3,5-dibenzylphenyloxide** in 100 mL of anhydrous **toluene**. Add **50g N-bromosuccinimide (NBS)** and stir at 0°C with 2 drops of **benzoyl peroxide**. After 4 hours, warm to room temp and stir for 12 hours. Filter and extract with **sodium bisulfite**, then dry and evaporate.
Step 2: Dissolve **20g of product** in 150 mL of **acetonitrile**. Add **30g potassium carbonate** and **5g oxazolidone**, then reflux at 85°C for 16 hours. Filter, evaporate, and isolate.
Step 3: Add **10g of intermediate** with **15g N-phenylethylamine** in **dichloromethane**. Add **2g diisopropylcarbodiimide (DIC)**, stir at 0°C for 2 hours, then room temp for 24 hours. Wash, dry, and purify.
Step 4: Dissolve in **THF**, add **phosphorus pentoxide**, heat, filter, and recrystallize.
Final Step: Dissolve in **HCl** in **methanol**, evaporate, and dry to form the HCl salt.
Thx